Archive for 'Diagnostics' Category:

NeedleBlood 200sq
By Juan F Roman: Tuesday 18th July, 2017

Liquid biopsy shows great promise for cancer diagnostics

The recent results from tests run at the Francis Crick Institute in London, after a trial funded by Cancer Research UK , present further evidence of the ability of liquid biopsy to detect the presence of minute samples of circulating tumour DNA. The advantage of liquid biopsy for patients and healthcare providers is that it […]

DNA
By Pari Datta: Friday 28th April, 2017

The promise of improving outcomes for cancer patients through the liquid biopsy

This week’s publication in Nature  is another major step towards the promise of the liquid biopsy. The study shows that the residual DNA fragments from cancer cells which are found in a patient’s blood could really have a role in real-time monitoring of a patient’s cancer in the future. These fragments were used to track […]

Systems Engineering
By Dr Rodrigo Zapiain: Wednesday 16th November, 2016

Developing Diagnostics and Point Of Care Equipment – Project Management and Systems Engineering: Two sides of the same coin

In this series of blogs about systems engineering we have  covered five key elements so far. 1) Understanding and analysis of project requirements, 2) Functional analysis, and system architecture definition  3) Design generation and detail design , 4) System integration and interface management and 5) System Verification and Validation.  In this blog, I will cover the special influence the Systems Engineering approach has […]

POC device development is challenging
By Juan F Roman: Wednesday 12th October, 2016

7 criteria that could define the commercial success of a POC test

The development of point-of-care (POC) devices is probably one of the most challenging endeavours a medical device developer will face. This is not only because of the technical challenges that need to be overcome but also because of the disruptive nature of POC testing and the risks this poses to any commercialisation plan. However, if you […]

Imaging
By Pari Datta: Wednesday 10th August, 2016

Current challenges in cancer diagnosis and treatment

The future of cancer diagnostics requires us to ask an ever-increasing number of questions – as more information is required about a cancer to define the right treatment for the patient. The earlier this information is available, the more likely the treatment is to be successful. But the number of questions that can be answered […]

Systems Engineering
By Dr Rodrigo Zapiain: Tuesday 26th July, 2016

Developing Diagnostics and Point Of Care Equipment – System Verification and Validation

In this series of blogs about systems engineering we have so far covered four key elements. 1) Understanding and analysis of project requirements, 2) Functional analysis, and system architecture definition  3) Design generation and detail design and 4) System integration and interface management. In this blog, I will share some thoughts about the process of validating and verifying that […]

Systems Engineering
By Dr Rodrigo Zapiain: Thursday 30th June, 2016

Developing Diagnostics and Point Of Care Equipment – System Integration and Interface Management

In this series of blogs about systems engineering we have so far covered three key elements. 1) Understanding and analysis of project requirements, 2) Functional analysis, and system architecture definition and 3) Design generation and detail design. In this blog, I will share some thoughts about integrating all the different components and sub-systems into the system […]

Blood glucose monitoring
By Bo Petersson: Monday 13th June, 2016

Wearables –an additional tool for preventing hypoglycaemic events?

The use of wearables for the monitoring of digital biomarkers associated with chronic diseases is starting to change how disease management is carried out. More accurate and relevant data is seen as a tool that can: help pharmaceutical companies assess the effectiveness of their treatments – as it allows more accurate measurement of outcomes during […]

Systems Engineering
By Dr Rodrigo Zapiain: Tuesday 17th May, 2016

Developing Diagnostics and Point Of Care Devices – Design Generation and Detail Design

In the previous Blog of the series, we introduced the concept of System Architecture and its importance in Diagnostics and Life Sciences equipment. In this issue, we will explore how this architecture leads to the creation of a specific physical structure that defines a system capable of delivering the desired functional performance. We will discuss […]

Systems Engineering
By Dr Rodrigo Zapiain: Monday 11th April, 2016

Developing Diagnostics and Point Of Care Devices – Functional Analysis and System Architecture definition

In past blogs, we have explored the principles of Systems Engineering and the importance of proper identification and definition of Project Requirements for successful diagnostics device development for Point of Care testing and design of Life Sciences instrumentation. But what happens once you have your list of requirements? Do you start developing a solution? No just […]